(1).jpg "Vickie Kimler")
Laboratory Manager
Ocular Structure and Imaging Facility
Eye Research Institute
428/431 Dodge Hall
[email protected]
Education
B.S. from Eastern Michigan University
1981, Ypsilanti, Michigan, United States
Biology/Psychology
M.S. from Eastern Michigan University
1985, Ypsilanti, Michigan, United States
Biology with Physiology Concentration
Ph.D. from Wayne State University
1993, Detroit, Michigan, United States
Cell Biology/Neurosciences Interdisciplinary Program
Postdoctoral from Rosalind Franklin University
1994, North Chicago, Illinois, United States
Muscle Physiology
Postdoctoral from The Cleveland Clinic Foundation
1995, Cleveland, Ohio, United States
Cardiac Structure and Function
Dr. Vickie Kimler comes to us from a recent position as research scientist from the Center for Integrative Metabolic and Endocrine Research at Wayne State University, where she performed all electron microscopic projects for the Center from 2009-2014. Before that Vickie was employed as a vocational rehabilitation instructor and case manager at Broe Rehabilitation Services after receiving her C.M.A. associate’s degree at Baker College of Auburn Hills in 2008. She also has worked as the laboratory manager in the Sleep Research Laboratory at the Veteran’s Administration Medical Center in Detroit after five years assistant professorship teaching pathophysiology and physiology to nursing students at the University of Detroit Mercy. During this time, Vickie shared research with Dr. Charles R.C. Marks in the Program in Exercise Sciences at Oakland University with minor funding. Vickie was appointed adjunct affiliate Clinical Associate Professor of Health Sciences at Oakland University for her mentorship of several M.S. students and for the research on exercise performance and fruit antioxidant nutrition. After her postdoctoral studies commencing in 1995, Vickie was assistant professor at Mercyhurst College teaching health sciences classes in the Biology Department. She ran a well-funded laboratory with $85.5K in grant monies from the Hess-Roth-Kaminsky Urological Foundation, Hamot Hospital Second Century Fund and the Hank and Peggy Pietraszek Fund Programs. Vickie has over fifteen years’ experience in electron microscopy from her doctoral studies on pigmentary organelle translocation in fishes all the way to lipid droplet physiology and morphology investigations, both at WSU, before her work at the ERI’s OSI. It is interesting to note that her career also began in eye research, where she was research coordinator on all projects with and for residents under the mentorship of the late Leslie J. Fisher, PhD, at the Henry Ford Hospital Department of Ophthalmology during 1935-1985. Dr. Fisher and his team examined the effect of tuftsin on rod outer segment phagocytosis in the retina in human, bovine and murine models.
Publications Since 2000
Ramseyer VD, Kimler VA, Granneman JG. Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytes. (2017) Mol Metab. pp 57-60
Dean, I., Dzinic, S.H., Bernardo, M. M., Zou, Y., Kimler, V., Li, X-h., Alexander Kaplun, A., Granneman, J., Mao, G-z. and Sheng, S-j. (2017) The Secretion and Biological Function of Tumor Suppressor Maspin as an Exosome Cargo Protein. Oncotarget, 8(5), 8043-8056.
Granneman, J.G., Kimler, V.A., Zhang, H.-m., Ye, X.-q., Luo, X.-x., Postlethwait, J.H. and Thummel, R. (2017) Lipid Droplet Biology and Evolution Illuminated by the Characterization of a Novel Perilipin in Teleost Fish. eLife, 6, e21771, 1-22.
Milstein, M., Kimler V.A., Ghatak, C., Ladhokin, A.S. and Goldberg, A.F.X. (2017) An Inducible Amphipathic Helix Within the Intrinsically Disordered C-terminus is not Required for Protein Biosynthesis, Trafficking or GARP2 Interaction, but can Participate in Membrane Curvature Generation by Peripherin-2/rds. Journal of Biological Chemistry, 292(19), 7850-7865.
Granneman, J.G., Kimler, V.A. and Moore, H.P. (2010) Cell Biology Symposium:Imaging the Organization and Trafficking of Lipolytic Effectors in Adipocytes. Journal of Animal Research, 89(3):701-710.
Sánchez-Moreno, C., Kimler, V.A., Cordts, F.L., Cady, J.A., Weller, M.A., Dumper, J.W., Williams, P., Pink, F.E., Rasmussen, H.M., Jiménez-Escrig, A., Martin, A., Joseph, J.A., and Marks, C.R.C. (2007) Effect of a Blueberry Nutritional Supplement on Macronutrients, Food Group Intake and Plasma Vitamin E and Vitamin C in US Athletes.International Journal of Food Sciences and Nutrition, 59(4), 327-338.
Kimler, V.A., Tracy, M., Ollie, C.D., Langer, R.M., Montante, J., Marks, C.R.C., Freeman, D.K., Hough R.A. and Taylor J.D. (2004a) Characterization of Melanophore Morphology by Fractal Dimension Analysis, Pigment Cell Research, 17(2), 165-172.
Kimler, V.A., and Taylor, J.D. (2002) Morphological Studies on the Mechanisms of Pigmentary Organelle Transport in Fish Xanthophores and Melanophores. Journal of Microscopy and Technique, 58(6):470-480.
Kimler, V.A., Palazzolo, K.L., Anne, P., Haddad, M.M., Lee, J.P., Harkins, C., Vallarapu, B., and Taylor, J.D. (2002) Morphological Studies on Microfilaments and their Organizing Center in Killifish ( Fundulus heteroclitus L.) Melanophores. Pigment Cell Research, 15:1-7.
Membership
Michigan Microscopy and Microanalysis Society, President, 2013-2015, 2017-2019