Department of Chemistry

Mathematics and Science Center,
Room 260
146 Library Drive
Rochester, MI 48309-4479
(location map)
(248) 370-2320
fax: 370-2321

Journal Cover Highlights

Prof. Kodi Beyeh's articles were highlighted by the cover art in two top ACS journals.  View more at:

A study of CH–π interaction between resorcinarene (A), pyridine (B), and carboxylic acids (Cn) led to formation and characterization of the desired A•B•Cn ternary assemblies.

Host-Guest Interactions of Sodiumsulfonatomethyleneresorcinarene and Quaternary Ammonium Halides: An Experimental-Computational Analysis of the Guest Inclusion Properties.

Also, a French/Polish/US team led by Prof. Amit Adhikary reported studies that determined the nature and directionality of the hole-transfer pathways between DNA backbone and base in phosphorodithioate systems and identification of the radicals involved.  The cover and article can be viewed at Chemistry A European Journal.

NIH awards grant to investigate neurodegenerative disorder

NIH awarded Dr. Adam Avery a grant to study the molecular and cellular mechanisms underlying the human neurodegenerative disease Spinocerebellar Ataxia Type 5.

New Instrumentation - Electron Spin Resonance

In an effort spearheaded by Prof. Amit Adhikary the department received a NSF MRI grant that has funded the purchase of a new ESR instrument with cryogenic studies accessories.  The instrument is up and running, and contributes to the studies of DNA damage. 

Department of Chemistry

The Department of Chemistry offers a full curriculum in undergraduate and graduate education in the chemical sciences. 

Our faculty are committed to providing the highest quality teaching and research. Research participation by undergraduates is a distinctive part of the department's activity. Our students have the opportunity to carry out research projects at the forefront of chemical, biochemical, and environmental research. Undergraduates often publish their research in internationally recognized journals as well as present their work at national meetings of the Student Affiliates of the American Chemical Society

The department is housed in the Mathematics and Science Center (MSC) with advanced research laboratory facilities and renovated teaching laboratories. We are well-equipped with modern instrumentation for chemical research and teaching. Major instruments include high-performance computational chemistry facilities, advanced instrumentation such as Nuclear Magnetic Resonance (NMR), Electron Spin Resonance (ESR), Time-of-Flight (LC TOF-MS) and Gas Chromatography (GC-MS)-mass spectrometers, Inductively Coupled Plasma Optical Emission (ICP-OES), Infrared (IR), UV-visible and fluorescence spectrometers, dry boxes, a solvent purification system, and instruments for biochemistry such as flow cytometers, ultracentrifuges, and cell culture facilities. Recently, Recently, a new spinning disk laser confocal microscope and droplet digital polymerase chain reaction (ddPCR) instrument were installed.




Transcript
Alzheimer’s disease is a progressive brain disorder, which affects mainly memory and thinking skills and that currently has no cure.

I started working on Alzheimer’s disease after taking Dr. Martic’s class last year and since I have a background in pharmacy, thought it would be incredible to give my contribution to research and finding a cure for disease.

I’m Albanian. And I left my home country after high school. When I was nineteen I moved to Italy to Rome to study pharmacy. After finishing pharmacy, I worked as a pharmacist for six years and I lived there for about twelve years before moving to the United States about two years ago. I first moved to study English for a whole year but after one semester I got accepted into a chemistry program, master’s program.

So here we have different samples of the protein of interest that will be loaded on the gel and then we will apply an electrical field to separate the protein based on their molecular weight.

I hope to find, in this sample, a reduced phosphorylation in the presences of the antibody compared to the sample where the protein isn’t phosphorylated in the absence of the antibody.

It will help us to better understand tau protein by chemistry the effects of antibodies on tau protein phosphorylation and maybe find a cure for Alzheimer’s disease.