The Institute for Stem Cell and Regenerative Medicine (ISCRM) is a bi-institutional center composed of investigators from Beaumont Health System and Oakland University. Building on more than 10 years of history of stem cell research at OU and William Beaumont, the ISCRM was created in 2010 with a small contribution from both institutions with a mission to utilize human stem cell, tissue engineering and regenerative technologies to treat human injuries, disease and disorders.
The ISCRM promotes and provides a comprehensive and coordinated "bench to bedside" approach to regenerative medicine, including basic biomedical and clinical research, tissue engineering and regenerative approaches, and the development and administration of stem cell-based therapies to patients.
The vision of the ISCRM is to rapidly translate cutting-edge stem cell and tissue engineering research into the clinic and for commercial applications for treating human diseases and disorders.
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McKee, C, Hong, Y, Yao, D, Chaudhry, GR. 2017. Compression induced chondrogenic differentiation of embryonic stem cells in 3-D PDMS scaffolds. Tissue Engineering Part A. doi: 10.1089/ten.TEA.2016.0376.
Beeravolu N, Brougham J, Khan I, McKee C, Perez-Cruet M, Chaudhry GR. 2017. Human Umbilical Cord Derivatives Regenerate Intervertebral Disc. Journal of Tissue Engineering and Regenerative Medicine. doi: 10.1002/term.2330.
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Alghamdi S, Khan I, Beeravolu N, Mckee C, Thibodeau B, Wilson G, Chaudhry GR. 2016. BET protein inhibitor JQ1 inhibits growth and modulates WNT signaling in mesenchymal stem cells. Stem Cell Research and Therapy. 7:22.